Description
IFN-gama is the only member of the type II interferon family, which is mainly secreted by natural killer T cells, CD4 cells and CD8 cells. IFN-γ has antiviral activity and can directly inhibit viral replication. In addition, IFN-γ can also act as a strong activator of macrophages and participate in immune regulation. Abnormal expression of IFN-γ can lead to some autoimmune and inflammatory diseases.
Product Properties
|
Synonyms |
IFNG;IFN-r |
|
Uniprot No. |
P01579 |
|
Source |
Recombinant Human IFN-γ Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Ala117-Ser269. |
|
Molecular Weight |
The protein has a predicted MW of 17.86 kDa. And it migrates as 25-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
<0.01 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
|
Reconstitution |
Centrifuge tubes before opening. The concentration of protein solution used for lyophilization is generally 1mg/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 ug/mL. |
Shipping and Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.