Description
IL-6 is similar to other interleukins in that it has a compact globular folding structure and is held in place by two disulfide bonds. The cysteine involved in forming these two disulfide bonds is highly conserved. IL-6, expressed by a variety of cells, regulates cell growth and differentiation in various tissues and is an important pro-inflammatory and immunomodulatory cytokine.
Product Properties
|
Synonyms |
Interleukin-6,BSF2,HSF,IFNB2 |
|
Uniprot No. |
P05231 |
|
Source |
Recombinant Human IL-6 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Val30-Met212. |
|
Molecular Weight |
The protein has a predicted MW of 22.75 kDa. And it migrates as 25-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
<0.1 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
|
Concentration |
1mg/ml. |
Shipping and Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.